The Official Patient's Sourcebook on Tooth Decay by Icon Health Publications

By Icon Health Publications

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The National Health Information Center (NHIC) The National Health Information Center (NHIC) offers a free referral service to help people find organizations that provide information about tooth decay. gov/NHIC/ or contact an information specialist by calling 1-800-336-4797. DIRLINE A comprehensive source of information on associations is the DIRLINE database maintained by the National Library of Medicine. The database comprises some 10,000 records of organizations, research centers, and government institutes and associations which primarily focus on health and biomedicine.

Clinical trials are carried out in three phases: · Phase I. Researchers first conduct Phase I trials with small numbers of patients and healthy volunteers. If the new treatment is a medication, researchers also try to determine how much of it can be given safely. · Phase II. Researchers conduct Phase II trials in small numbers of patients to find out the effect of a new treatment on tooth decay. · Phase III. Finally, researchers conduct Phase III trials to find out how new treatments for tooth decay compare with standard treatments already being used.

If you choose to participate in a clinical trial, you will not know which group you will be appointed to. The chance of any patient getting the new treatment is about 50 percent. You cannot request to receive the new treatment instead of the placebo or sham treatment. Often, you will not know until the study is over whether you have been in the treatment group or the control group. This is called a “masked” study. In some trials, neither researchers nor patients know who is getting which treatment.

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