Research Methods in Neurochemistry: Volume 6 by Mary J. Voaden (auth.), Neville Marks, Richard Rodnight

By Mary J. Voaden (auth.), Neville Marks, Richard Rodnight (eds.)

Show description

Read Online or Download Research Methods in Neurochemistry: Volume 6 PDF

Best research books

Research Agendas in EU Studies: Stalking the Elephant (Palgrave Studies in European Union Politics)

Prime students discover the complicated questions coming up from the continued transformation of Europe in the course of the deepening and widening results of ecu integration. in response to authoritative analyses, the ebook takes account of the numerous nationwide, transnational and foreign procedures and contexts during which ecu integration has turn into embedded.

Perspectives on Scientific Argumentation: Theory, Practice and Research

Argumentation—arriving at conclusions on a subject matter via a technique of logical reasoning that comes with debate and persuasion— has in recent times emerged as a important subject of debate between technological know-how educators and researchers. there's now a company and normal trust that fostering argumentation in studying actions can strengthen scholars’ serious pondering and reasoning abilities, and that dialogic and collaborative inquiries are key precursors to an engagement in medical argumentation.

Ciba Foundation Symposium 134 - Research and the Ageing Population

This overseas symposium makes a speciality of the contributions that biomedical examine is making to the availability of right health and wellbeing take care of the expanding numbers of aged humans in all nations, built and constructing. contemporary, encouraging advancements within the components of malignancy, dementia, osteoporosis, and heart problems are emphasised.

Additional resources for Research Methods in Neurochemistry: Volume 6

Example text

The series of changes are known as the electroretinogram (ERG; Fig. 7). , 1983). , in man), the active electrode is placed on the cornea, and a reference electrode is placed on the scalp, effectively behind the eye. Larger responses, with the noise level greatly reduced, are obtained experimentally if the active electrode is placed in the vitreous and the reference electrode in the orbit directly behind the eye. High-impedance electrodes are needed, as the changes in potential are relatively slow: silver/silver chloride electrodes are often used.

According to how much the eye collapses (rats and mice), it should be possible to see whether or not the vitreous is present. If present, it can be removed intact by gripping into the globe with blunt forceps, with one taking care not to contact the neural tissue. A similar procedure may prove suitable for larger eyes. Alternatively, according to species, it may be necessary to remove the gel, in portions, with wicks of filter paper or cotton swabs. In some species, unacceptable damage may be done to the retina if attempts are made to remove the vitreous in toto.

1982; Fukuda, 1982). A. Retinal Fractionation by Cell Degeneration Apart from techniques localizing activities to specific cell types, the retina is also well suited to what might be described as "negative" investigation, in which the study of tissue depleted of specific cell populations gives, by comparison with the norm, an indication of the characteristics associated with the missing cells. Since the retina is "anchored" within the eye, loss of cells, in general, leads to a narrowing of tissue thickness but not of tissue area.

Download PDF sample

Rated 4.88 of 5 – based on 49 votes