Protein-protein Interactions and Networks: Identification, by Peter Uetz, Björn Titz, Gerard Cagney (auth.), Anna

By Peter Uetz, Björn Titz, Gerard Cagney (auth.), Anna Panchenko, Teresa Przytycka (eds.)

The organic interactions of dwelling organisms, and protein-protein interactions particularly, are astonishingly varied and current various demanding situations to fashionable biomolecular study as a result of their complexity. research of styles and rules governing those interactions has triggered a fast improvement of computational tips on how to establish protein interplay companions and to appreciate the jobs of person parts of protein interplay networks in cellphone functions.

This ebook integrates varied techniques from bioinformatics, biochemistry, computational research and platforms biology to provide the reader a accomplished international view of the various facts on protein-protein interactions and protein interplay networks. It brings jointly the descriptions of experimental innovations and expounds on varied computational algorithms for protein community research and prediction of protein and area interactions, with every one bankruptcy containing an outline of the matter, a evaluate of equipment and algorithms, an inventory of assets and present conclusions.

Features

• stories experimental thoughts for id of protein interactions

• Discusses protein interplay databases and strategies of integrating info from varied sources

• Describes computational how to expect protein and area interplay companions

• Explores the houses of interplay interfaces and highlights ways to version the meeting of protein complexes

• Examines the topological and dynamical homes of protein interplay networks and offers the instruments for comparative research of those networks

Written by way of prime specialists, Protein-protein Interactions and Networks offers a extensive, thorough and multidisciplinary assurance of this box. it is going to be important to researchers from academia and the bioinformatics undefined, in addition to a very good auxiliary textual content for graduate scholars learning the topic.

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Additional resources for Protein-protein Interactions and Networks: Identification, Computer Analysis, and Prediction

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U. S. A. 95(20): 11810–11815. Ong, S. , Kristensen, D. , Pandey, A. and Mann, M. (2002). Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol. Cell. Proteomics 1(5): 376–386. Patil, A. and Nakamura, H. (2005). Filtering high-throughput protein-protein interaction data using a combination of genomic features. BMC Bioinformatics 6: 100. Pawson, T. and Nash, P. (2003). Assembly of cell regulatory systems through protein interaction domains.

Fields, S. and Rothberg, J. M. (2000). A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403(6770): 623–627. Uetz, P. and Stagljar, I. (2006). The interactome of human EGF/ErbB receptors. Mol. Syst. Biol. 2: 2006 0006. Vojtek, A. , Hollenberg, S. M. and Cooper, J. A. (1993). Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74(1): 205–214. Vollert, C. S. and Uetz, P. (2004). The phox homology (PX) domain protein interaction network in yeast.

2006). A novel conserved assembly factor of the bacterial flagellum. J. Bacteriol. 188: 7700–7706. , Schlesner, M. and Uetz, P. (2004). What do we learn from high-throughput protein interaction data? Expert Rev. Proteomics 1(1): 111–121. , Dong, Y. , Rajagopala, S. , Fossum, E. and Haas, J. (2006). Herpesviral protein networks and their interaction with the human proteome. Science 311(5758): 239–242. , James, D. and Zeller, R. (1996). Molecular interaction between limb deformity proteins (formins) and Src family kinases.

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