Clozapine - A Medical Dictionary, Bibliography, and by Icon Health Publications

By Icon Health Publications

It is a 3-in-1 reference booklet. It provides an entire clinical dictionary overlaying 1000s of phrases and expressions with regards to clozapine. It additionally supplies vast lists of bibliographic citations. ultimately, it offers details to clients on how you can replace their wisdom utilizing numerous web assets. The booklet is designed for physicians, clinical scholars getting ready for Board examinations, clinical researchers, and sufferers who are looking to familiarize yourself with examine devoted to clozapine. in case your time is effective, this ebook is for you. First, you won't waste time looking the web whereas lacking loads of appropriate info. moment, the publication additionally saves you time indexing and defining entries. ultimately, you won't waste time and cash printing hundreds of thousands of websites.

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Extra resources for Clozapine - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

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Scientific questions about the role of the receptor in the pathophysiology of schizophrenia, as well as the issue of its utility as a therapeutic target, cannot be adequately addressed without the development of strategies for selective activation of the a7 receptor in human subjects. Therefore, included in the experimental plan are Phase 1, proof of principle, tests for a new a7 nicotinic agonist, 3-(2,4 dimethoxybenzylidene) anabaseine (DMXB-A). ; Associate Professor; Psychiatry; Duke University Durham, Nc 27710 Timing: Fiscal Year 2002; Project Start 12-DEC-2001; Project End 30-NOV-2006 Summary: Nicotine is self-administered via cigarette smoking by the great majority of patients with schizophrenia.

Goo's research plan involves continuation of his study of glutamatergic agents in schizophrenia and of the role of glutamatergic activity in the therapeutic action of atypical antipsychotics. He will devote the period of the career development award to completing on-going RO1-funded controlled trials of NMDA receptor agonists, initiating trials of new glutamatergic agents (D-serine and an Ampakine) and developing expertise with new research tools and developing collaborations to apply to his research, including neuroimaging, spectroscopy, transcranial magnetic stimulation and genetics.

The assay can be scaled up applying FLIPR or potentially the cell-array platform. In this feasibility study, we will apply the novel cAMP assay to measure intrinsic efficacy of several partial agonists against the dopamine D2 receptor, and to determine relative potency and efficacy of the most common antipsychotic drugs, olanzapine, quetiapine, clozapine, and aripiprazole against several potential GPCR targets. The long-term goal of the project is to characterize currently important antipsychotics against all biogenic amine receptors and other potential receptor targets to provide a solid receptor profile of antipsychotics.

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