Cane sugar engineering by Peter Rein

By Peter Rein

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Mean Circulatory, Systemic, and Pulmonary Pressures The mean circulatory pressure is the pressure in the circulation when, in the absence of changes in arterial or venous tone, the pressure is equal everywhere. Guyton, Jones, and Coleman (1973) initially measured the mean circulatory pressure by fibrillating the heart and rapidly pumping volume from the arteries into the veins so that pressures were equalized everywhere within 7 to 10 seconds. In the dog they found the mean circulatory pressure to be 7 mm Hg, a remarkably constant value.

189:609-615. Johnson, P. , and Hanson, K. M. 1963. Relation between venous pressure and blood volume in the intestine. Am. 1. Physiol. 204:31-34. Levy, M. N. 1979. The cardiac and vascular factors that determine systemic blood flow. Circ. Res. 44:739-746. Lindsey, A. , Banahan, B. , Cannon, R. , and Guyton, A. C. 1957. Pulmonary blood volume of the dog and its changes in acute heart failure. Am. 1. Physiol. 190:45. Lindsey, A. , and Guyton, A. C. 1959. Continuous recording of pulmonary blood volume, and pulmonary pressure and volume changes during acute right or left ventricular failure.

2). Once the plateau level is reached, this parameter is meaningless, as venous return has reached a maximum. We conclude from these studies that venoconstriction in the whole circulation increases the venous resistance but elevates the plateau. This has been confirmed in conscious dogs by Appleton and co-workers (1985). Caldini and colleagues (1974) first proposed that the venous circulation might consist of more than one compartment, with capacitance and resistance parameters that could not be added in a linear fashion.

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