Bronchiolitis - A Medical Dictionary, Bibliography, and by Icon Health Publications

By Icon Health Publications

This can be a 3-in-1 reference ebook. It offers a whole clinical dictionary masking hundreds of thousands of phrases and expressions in terms of bronchiolitis. It additionally offers huge lists of bibliographic citations. eventually, it offers info to clients on tips on how to replace their wisdom utilizing a variety of net assets. The publication is designed for physicians, clinical scholars getting ready for Board examinations, clinical researchers, and sufferers who are looking to familiarize yourself with study devoted to bronchiolitis. in the event that your time is efficacious, this ebook is for you. First, you won't waste time looking the web whereas lacking loads of proper info. moment, the ebook additionally saves you time indexing and defining entries. eventually, you won't waste time and cash printing 1000's of websites.

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Extra resources for Bronchiolitis - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

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We have previously shown that patients who develop donor antigen-specific hyporesponsiveness have decreased incidence of late acute rejection episodes, decreased chronic rejections (biopsy proven in kidney transplant recipients, coronary artery disease on angiogram in heart transplant recipients, and of obliterative bronchiolitis in lung transplant recipients), and improved long term graft survival. The goal of the current study is to determine whether those who have developed donor antigen-specific hyporesponsiveness can have the same excellent long-term outcome after prednisone withdrawal ( in kidneys and heart recipients) or conversion to nebulized prednisone (in lung transplant recipients).

The spectrum of illness induced directly by the viruses is very broad, ranging from mild colds and simple ear infections to more serious and sometimes life-threatening diseases such as bronchiolitis, pneumonia, and asthma. In spite of the importance of diagnosing and treating these viral infections, current diagnostic methods of physical exam or rapid immunoassays or culture in reference laboratories do not provide the accuracy, sensitivity, or timely information that the primary care physician needs for treatment.

Recently, the RSV fusion (F) protein was shown to be a TLR4 agonist. In vitro, cotton rat macrophages respond to LPS and F protein to elicit the same spectrum of inflammatory genes, although the F protein is less potent. The overall hypothesis to be tested is that the interaction of F protein with TLR4 is essential for establishment of a Thl-type milieu and that formalin fixation of RSV destroys the capacity of F to interact with TLR4, resulting in a Th2-type response. This proposal details novel experimental approaches: (i) to evaluate the contribution and regulation of F protein signaling through TLR4 to the development of a Th1-type cytokine profile, (ii) to determine the role of TLR4 in the development of RSV-mediated disease in vivo, and (iii) to determine if polymorphic forms of TLR4 previously associated with airway hyporesponsiveness to LPS exhibit diminished sensitivity to F protein and if they are overrepresented in a population at high risk for RSV.

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